Table 3. Permeation of hyp-polydendron nanoprecipitates with varying G2–PEG16 molar ratios through Caco-2 monolayers.
| G2–PEG16 molar ratio |
P
app (cm s–1) |
P app ratio (A > B)/(B > A) | |
| Apical > Basolateral (A > B) | Basolateral > Apical (B > A) | ||
| 100 : 0 | 1.763 × 10–5 | 1.538 × 10–6 | 11.4605 |
| 75 : 25 | 2.613 × 10–5 | 2.056 × 10–6 | 12.7123 |
| 50 : 50 | 5.271 × 10–5 | 5.555 × 10–6 | 9.4872 |
| 25 : 75 | 4.135 × 10–5 | 4.684 × 10–6 | 8.8279 |
| 10 : 90 | 4.042 × 10–4 | 4.580 × 10–5 | 8.8255 |
| 0 : 100 | 2.060 × 10–5 | 3.188 × 10–6 | 6.4626 |
| Aq. Nile Red a | 2.371 × 10–5 | 6.384 × 10–6 | 3.7140 |
a<1% v/v DMSO/water solution.