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. 2017 Jul 6;6(7):e005025. doi: 10.1161/JAHA.116.005025

Table 2.

Study Characteristics of the Included Studies

Author Country Cohort Name Follow‐up Total Participants Total CVD Patients CVD Type Adjustment
Gkrania‐Klotsas et al, 201218 UK Cancer–Norfolk Cohort 12 11 022 1356 IHD, cardiovascular death Age, sex, smoking, SBP, DBP, LDL, HDL, triglycerides, prevalent diabetes mellitus, family history, educational level, occupation, Townsend index, use of antihypertensives, statins, or glucose‐control medications, alcohol use, body mass index, C‐reactive protein
Haider et al, 200212 US Framingham Heart Study cohort 10 1187 199 IHD, stroke, cardiovascular death Age, sex, body mass index, total cholesterol and HDL, diabetes mellitus, smoking, and hypertension
Fagerberg et al, 199916 Sweden NR 6.5 152 58 IHD, stroke, cardiovascular death Smoking and the presence of previous CVD and for group allocation in the underlying multiple risk factor intervention study
Simanek et al, 201119 US National Health and Nutrition Examination Survey 13.8 14 153 1542 Cardiovascular death Age, sex, race/ethnicity, country of origin, education level, body mass index (kg/m2), smoking status, diabetes mellitus status, and C‐reactive protein level
Smieja et al, 200313 Canada Heart Outcomes Prevention Evaluation 4.5 3168 905 IHD, stroke, cardiovascular death Age, sex, smoking, ramipril, diabetes mellitus, hypertension, and hypercholesterolemia
Savva et al, 201315 UK ERSC Healthy Aging Study 18 511 138 Cardiovascular death Date of birth and sex
Roberts et al, 201014 US Sacramento Area Latino Study on Aging 9 1329 220 Cardiovascular death Age, sex, and education, myocardial infarction, congestive heart failure, stroke, dementia, liver/renal disease, diabetes mellitus, malignancy, and leukemia or lymphoma
Elkind et al, 201010 US The Northern Manhattan Study Mitchell 7.6 1625 67 Stroke Age, sex, race/ethnicity, high school education, systolic blood pressure, HDL, LDL, blood glucose level, moderate alcohol use, cigarette smoking status, waist circumference, physical activity, and coronary artery disease
Spyridopoulos et al, 201620 UK The Newcastle 85+ study 6 749 184 Cardiovascular death Sex
Corrado et al, 200621 Italy NR 5 668 120 IHD, stroke, cardiovascular death Age, male sex, obesity, hypertension, diabetes mellitus, smoking habit, family history of CAD, and dyslipidemia

CAD indicates coronary artery disease; CVD, cardiovascular disease; DBP, diastolic blood pressure; ERSC Economic and Social Research Council; HDL, high‐density lipoprotein; IHD, ischemic heart disease; LDL, low‐density lipoprotein; NR, not reported; SBP, systolic blood pressure.