Yield of obstructive coronary artery disease (CAD) among the different index cardiac noninvasive diagnostic testing strategies stratified according to low, intermediate, and high modified Framingham risk. Multivariable model displaying the odds ratios and 95% confidence intervals of the yield of obstructive CAD among the different index cardiac noninvasive diagnostic tests in patients who underwent invasive angiography for the assessment of stable CAD (GXT is the reference test). Adjusted for age, sex, presence of diabetes mellitus, dyslipidemia, hypertension, income quintile, resting ECG abnormalities, Charlson comorbidity index score, serum creatinine, smoking history, Canadian Cardiovascular Society class angina symptom scale, chronic obstructive pulmonary disease, peripheral vascular disease, and modified Framingham risk score. CCTA indicates coronary computed tomography angiography; CI, confidence interval; GXT, graded exercise stress test; MPI, myocardial perfusion imaging; OR, odds ratio; stress echo, stress echocardiogram.