Table 1.
Characteristics of Patients Who Underwent Angiography for Evaluation of SCAD by Index Cardiac Noninvasive Test
| CCTA (n=113) | GXT (n=6742) | MPI (n=6877) | Stress Echo (n=1735) | Total (N=15 467) | P Value | |
|---|---|---|---|---|---|---|
| Age, y, mean±SD | 62.8±9.8 | 61.4±10.5 | 64.6±10.9 | 63.1±10.7 | 63.0±10.8 | <0.001 |
| Serum creatinine, μmol/L, mean±SD | 78.1±18.6 | 83.2±48.7 | 94.1±102.9 | 83.7±59.6 | 88.2±79.2 | <0.001 |
| Diabetes mellitus (%) | 39 (34.5) | 1981 (29.4) | 2672 (38.9) | 513 (29.6) | 5205 (33.7) | <0.001 |
| Dyslipidemia (%) | 77 (68.8) | 4309 (65.1) | 4898 (71.7) | 1136 (67.9) | 10 420 (68.4) | <0.001 |
| Hypertension (%) | 76 (67.3) | 4097 (60.8) | 4838 (70.4) | 1082 (62.4) | 10 093 (65.3) | <0.001 |
| Female sex (%) | 49 (43.4) | 2415 (35.8) | 2822 (41.0) | 696 (40.1) | 5982 (38.7) | <0.001 |
| Charlson score, mean±SD | 0.19±0.53 | 0.15±0.60 | 0.27±0.83 | 0.17±0.70 | 0.21±0.73 | <0.001 |
| Smoking (%) | 0.62 | |||||
| Current | 21 (18.9) | 1312 (19.6) | 1272 (18.6) | 349 (20.4) | 2954 (19.2) | |
| Former | 26 (23.4) | 1763 (26.3) | 1853 (27.1) | 451 (26.3) | 4093 (26.6) | |
| Never | 64 (57.7) | 3536 (52.8) | 3646 (53.2) | 890 (52.0) | 8136 (52.9) | |
| ST‐segment changes at rest on ECG (%) | 7 (6.2) | 697 (10.3) | 822 (12.0) | 179 (10.3) | 1705 (11.0) | <0.001 |
| CCS symptom scale, stable angina (%) | <0.001 | |||||
| 0 | 23 (20.4) | 1100 (16.3) | 1588 (23.1) | 441 (25.4) | 3152 (20.4) | |
| 1 | 18 (15.9) | 1286 (19.1) | 1325 (19.3) | 292 (16.8) | 2921 (18.9) | |
| 2 | 42 (37.2) | 2866 (42.5) | 2587 (37.6) | 695 (40.1) | 6190 (40.0) | |
| 3 or 4 | 32 (28.3) | 1490 (22.1) | 1377 (20.0) | 307 (17.7) | 3204 (20.5) | |
| Income quintile (%) | <0.001 | |||||
| 1 | 15 (13.4) | 1130 (16.8) | 1255 (18.3) | 354 (20.4) | 2754 (17.9) | |
| 2 | 18 (16.1) | 1359 (20.2) | 1479 (21.6) | 324 (18.7) | 3180 (20.6) | |
| 3 | 24 (21.4) | 1497 (22.3) | 1435 (20.9) | 337 (19.5) | 3293 (21.4) | |
| 4 | 26 (23.2) | 1370 (20.4) | 1386 (20.2) | 354 (20.4) | 3136 (20.3) | |
| 5 | 19 (25.9) | 1363 (20.3) | 1302 (19.0) | 363 (21.0) | 3057 (19.8) | |
| Framingham risk category (%) | 0.03 | |||||
| High | 30 (26.6) | 2076 (30.8) | 2248 (32.7) | 506 (29.2) | 4860 (31.4) | |
| Intermediate | 59 (52.2) | 3198 (47.4) | 3140 (45.7) | 816 (47.0) | 7213 (46.7) | |
| Low | 24 (21.2) | 1468 (21.7) | 1489 (21.7) | 413 (23.8) | 3394 (21.9) |
CCS indicates Canadian Cardiovascular Society; CCTA, coronary computed tomography angiography; GXT, graded exercise stress test; MPI, myocardial perfusion imaging study; SCAD, stable coronary artery disease; stress echo, stress echocardiogram.