Table 1.
High Risk (n=436) | Low Risk (n=1596) | P Value | |
---|---|---|---|
Age (y), mean (SD) | 60.8 (13.7) | 59.6 (12.7) | 0.09 |
Female | 109 (25) | 369 (23.1) | 0.41 |
GRACE risk score median (IQR) | 169 (148, 199) | 163 (144, 187) | <0.001 |
Creatinine (μmol/L), mean (SD) | 95.9 (36.6) | 94.2 (43.1) | 0.44 |
Medical history | |||
Hypertension | 206 (47.2) | 736 (46.1) | 0.67 |
Diabetes mellitus | 80 (18.3) | 252 (15.8) | 0.20 |
Dyslipidemia | 178 (40.8) | 674 (42.2) | 0.60 |
Prior MI | 74 (17.0) | 249 (15.6) | 0.49 |
Family history premature CAD | 85 (19.5) | 417 (26.1) | 0.004 |
Symptom onset to first medical contact (min), median (IQR) | 137 (69, 485) | 117 (62, 300) | 0.01 |
Reperfusion modality | <0.001 | ||
Primary PCI | 225 (51.6) | 682 (42.7) | |
Fibrinolysis | 147 (33.7) | 700 (43.9) | |
None | 64 (14.7) | 214 (13.4) | |
Length of hospital stay (days), median (IQR) | 6 (5, 10) | 4 (3, 6) | <0.001 |
In‐hospital events | |||
Death | 21 (4.8) | 31 (1.9) | <0.001 |
Re‐MI | 4 (0.9) | 4 (0.3) | 0.048 |
Cardiogenic shock or heart failure | 102 (23.4) | 116 (7.3) | <0.001 |
Cardiac arrest | 53 (12.2) | 126 (7.9) | 0.005 |
Non‐ICH major bleeding | 28 (6.4) | 101 (6.3) | 0.94 |
ICH | 1 (0.2) | 3 (0.2) | 0.86 |
Ischemic stroke | 1 (0.2) | 2 (0.1) | 0.62 |
In‐hospital medications | |||
Dual anti‐platelet therapy | 417 (95.6) | 1550 (97.1) | 0.12 |
ACE‐I/ARB | 412 (94.5) | 1506 (94.4) | 0.91 |
β‐Blocker | 425 (97.5) | 1532 (96.0) | 0.14 |
Cholesterol lowering | 414 (95.0) | 1499 (93.9) | 0.42 |
Numbers are n (%) unless specified otherwise; P values calculated by χ2 test (proportions), t test (means) or Wilcoxon‐Mann–Whitney test (medians). ACE‐I indicates angiotensin‐converting enzyme‐inhibitor; ARB, angiotensin receptor blocker; CAD, coronary artery disease; GRACE, Global Registry of Acute Coronary Events; ICH, intracranial hemorrhage; IQR, interquartile range; MI, myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST‐segment myocardial infarction.