Table 1.

Baseline Characteristics of the Study Population

Variables	Whole Population	NTN‐nAC (n=54, 25%)	HTN (n=93, 42%)	NTN‐rAC (n=73, 33%)	P Value
Clinical data
Age, y	69±13	59±14a, b	73±10c	72±9c	<0.0001
Male sex, %	71	62	76	70	0.20
Body mass index, kg/m2	28±5	27±5	29±5	27±4	0.07
Body surface area, m2	1.86±0.21	1.84±0.22	1.89±0.21	1.83±0.20	0.36
Blood pressure: systolic, mm Hg	135±18	114±10a, b	152±11c, b	129±7a, c	<0.0001
Blood pressure: diastolic, mm Hg	74±10	72±10a	79±11c, b	69±8a	<0.0001
Coronary artery disease, %	45	19a, b	50	56	<0.0001
Diabetes mellitus, %	25	21	28	22	0.52
Renal failure, %	12	8	14	12	0.58
Echocardiographic data
Peak aortic jet velocity, m/s	3.42±0.88	3.72±1.12a, b	3.24±0.70c	3.43±0.85c	0.006
Mean gradient, mm Hg	29±18	36±24a, b	25±12c	29±17c	0.001
Aortic valve area, cm2	1.06±0.30	1.07±0.33	1.12±0.29b	1.08±0.27a	0.005
Indexed aortic valve area, cm2/m2	0.57±0.16	0.59±0.18	0.59±0.15b	0.52±0.13a	0.009
Stroke volume, mL	82±17	88±19b	84±17b	76±11a, c	0.0001
Indexed stroke volume, mL/m2	44±7	48±8a, b	45±8c, b	41±5a, c	<0.0001
LV ejection fraction, %	65±6	65±6	65±7	64±6	0.80
Multidetector computed tomography data
Aortic valve calcification, AU	1677 [1466–1889]	1795 [1364–2260]	1665 [1340–1990]	1607 [1240–1975]	0.81d
Aortic valve calcification density, AU/cm2	374 [323–426]	418 [313–524]	354 [274–433]	369 [279–458]	0.62d

AU indicates Agatston units; HTN, hypertensive group; LV, left ventricle; NTN‐nAC, nonhypertensive–normal arterial compliance group; NTN‐rAC, nonhypertensive–reduced arterial compliance group.

^a P<0.05 from hypertension patients.

^b P<0.05 from NTN‐rAC patients.

^c P<0.05 from NTN‐nAC patients.

^dStatistical analysis stratified for sex.