Table 1.
The genes associated with the histological grade of ESCC
| Gene ID | Gene symbol | Mean G1 | Mean G2 | Mean G3 | P‐value |
|---|---|---|---|---|---|
| Positive correlation | |||||
| 66000 | TMEM108 | 5.418252604 | 7.329616234 | 7.916632334 | 7.32E‐05 |
| 339942 | C3orf47 | 5.267250937 | 6.198372806 | 6.497636229 | 0.0001191 |
| 56997 | CABC1 | 9.73904574 | 10.85150959 | 10.80083313 | 0.0002155 |
| 56994 | CHPT1 | 8.875674851 | 10.26804519 | 10.40381399 | 0.0002155 |
| 777 | CACNA1E | 1.946473596 | 3.895276537 | 4.321101557 | 0.0002574 |
| 2781 | GNAZ | 5.840673299 | 8.034275975 | 8.201352094 | 0.0002658 |
| 9915 | ARNT2 | 7.913558745 | 9.449765716 | 9.896500029 | 0.000382 |
| 84446 | BRSK1 | 5.704577382 | 7.004365547 | 7.552181962 | 0.000382 |
| 404217 | CTXN1 | 7.802343062 | 8.209738979 | 9.276647634 | 0.000382 |
| 7275 | TUB | 6.942555084 | 8.447990872 | 9.069991495 | 0.000382 |
| Negative correlation | |||||
| 3898 | LAD1 | 15.12740154 | 14.41469 | 13.78649 | 1.83E‐05 |
| 9220 | TIAF1 | 10.70008046 | 10.29157 | 9.869611 | 3.53E‐05 |
| 2256 | FGF11 | 11.26322247 | 10.4069 | 9.425334 | 4.05E‐05 |
| 771 | CA12 | 14.77830133 | 13.78284 | 12.64873 | 6.64E‐05 |
| 2769 | GNA15 | 12.81232253 | 11.95196 | 11.38613 | 6.64E‐05 |
| 3728 | JUP | 17.77287667 | 17.09011 | 16.28087 | 6.64E‐05 |
| 5317 | PKP1 | 17.23345646 | 16.1469 | 15.54338 | 6.64E‐05 |
| 5467 | PPARD | 13.54200932 | 12.72773 | 12.43948 | 6.64E‐05 |
| 1830 | DSG3 | 16.28279128 | 15.41625 | 14.01574 | 0.0001226 |
| 401647 | GOLGA7B | 10.61928628 | 9.106061 | 7.615288 | 0.0001226 |
G1, high differentiation; G2, middle differentiation; G3, low differentiation.