Figure 7.

Effects of 2‐deoxy‐d‐glu, 3‐O‐methyl‐d‐glu, d‐sorbitol, and d‐fructose on CYP11B2 mRNA expression. H295R cells were incubated with either 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ l‐glu, 450 mg·dL⁻¹ d‐glu, 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ 2‐deoxy‐d‐glu, 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ 3‐O‐methyl‐d‐glu, 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ d‐sorbitol, or 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ d‐fructose for 72 h. Data represent mean ± SEM (n = 4), percentage of 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ l‐glu, normalized by the β‐actin mRNA levels. *P < 0.01, vs. 100 mg·dL⁻¹ d‐glu plus 350 mg·dL⁻¹ l‐glu. **P < 0.01, vs. 450 mg·dL⁻¹ d‐glu.