Table 2.
Clinical Predictors of hsTnI at Baseline
| Unstandardized β Coefficient (95% CI) | P Value | |
|---|---|---|
| Whole cohort (n=1081) | ||
| Age, per 10 y | 0.23 (0.15, 0.31) | <0.001 |
| Body mass index, per 10 kg/m2 | 0.10 (0.05, 0.15) | <0.001 |
| Systolic blood pressure, per 10 mm Hg | 0.02 (0.00, 0.03) | 0.020 |
| Antihypertensive medications, yes | 0.15 (0.19, 0.19) | <0.001 |
| Current smoker, yes | −0.41 (−0.72, −0.09) | 0.012 |
| Diabetes mellitus, yes | 0.09 (−0.01, 0.19) | 0.064 |
| Those with lipids assessed (n=774) | ||
| Age, per 10 y | 0.20 (0.10, 0.30) | <0.001 |
| Total cholesterol, per 10 mg/dL | 0.01 (0.00, 0.01) | 0.014 |
| High‐density lipoprotein cholesterol, per 10 mg/dL | −0.05 (−0.06, −0.03) | <0.001 |
| Systolic blood pressure, per 10 mm Hg | 0.01 (−0.01, 0.02) | 0.212 |
| Antihypertensive medications, yes | 0.153 (0.10, 0.21) | <0.001 |
| Current smoker, yes | −0.55 (−0.96, −0.14) | 0.009 |
| Diabetes mellitus, yes | 0.14 (0.01, 0.27) | 0.035 |
Adjusted r 2 in whole cohort=0.12, P<0.001 and subset with lipids r 2=0.13, P<0.001. Multivariable model adjusted for age, body mass index (or total cholesterol and high‐density lipoprotein cholesterol), current smoker, diabetes mellitus, systolic blood pressure, and prescription of antihypertensive medications and treatment code (calcium or placebo). hsTnI indicates high‐sensitivity cardiac troponin I.