Table 6.
Ten‐Year Cardiac Events by SD and Quartiles of hsTnI
| No. of Events (%) | 10‐Years Follow‐up | ||
|---|---|---|---|
| Adjusted HR (95% CI) | P Value | ||
| Coronary heart disease events | |||
| Per SD of LN‐hsTnI | 153/1081 | 1.31 (1.11–1.54) | 0.001 |
| Q1 hsTnI (<3.6 ng/L) | 20/229 (8.0) | 1 (reference) | |
| Q2 hsTnI (3.6–4.4 ng/L) | 32/273 (11.7) | 1.26 (0.70–2.27) | 0.438 |
| Q3 hsTnI (4.5–5.7 ng/L) | 46/278 (16.5) | 1.86 (1.07–3.22) | 0.027 |
| Q4 hsTnI (≥5.8 ng/L) | 55/281 (19.6) | 2.03 (1.17–3.51) | 0.012 |
| Hard CHD eventsa | |||
| Per SD of LN‐hsTnI | 81/1081 | 1.64 (1.32–2.04) | <0.001 |
| Q1 hsTnI (<3.6 ng/L) | 8/249 (3.2) | 1 (reference) | |
| Q2 hsTnI (3.6–4.4 ng/L) | 17/273 (6.2) | 2.00 (0.82–4.88) | 0.128 |
| Q3 hsTnI (4.5–5.7 ng/L) | 19/278 (6.8) | 2.13 (0.89–5.13) | 0.091 |
| Q4 hsTnI (≥5.8 ng/L) | 37/281 (13.2) | 3.68 (1.59–8.55) | 0.002 |
| Heart failure events | |||
| Per SD of LN‐hsTnI | 44/1081 | 1.81 (1.36–2.40) | <0.001 |
| Q1 hsTnI (<3.6 ng/L) | 3/249 (1.2) | 1 (reference) | |
| Q2 hsTnI (3.6–4.4 ng/L) | 5/273 (1.8) | 1.46 (0.35–6.13) | 0.606 |
| Q3 hsTnI (4.5–5.7 ng/L) | 8/278 (2.9) | 2.26 (0.59–8.65) | 0.234 |
| Q4 hsTnI (≥5.8 ng/L) | 28/281 (10.0) | 6.93 (2.02–23.76) | 0.002 |
Cox regression models were adjusted for Framingham risk factors with body mass index and treatment code. CHD indicates coronary heart disease; HR, hazard ratio; hsTnI, high‐sensitivity cardiac troponin I.
a
Hard CHD is defined as myocardial infarction hospitalization or coronary heart disease death.