Table 1.
Baseline Characteristics (n=904)
| Characteristic | Result |
|---|---|
| Age, ya | 58±12b |
| Postmenopausal | 679 (76) |
| Non‐White race | 171 (19) |
| High school graduateb | 714 (80) |
| Diabetes mellitus | 223 (25) |
| History of dyslipidemia | 458 (55) |
| History of hypertension | 535 (59) |
| Family history of CAD | 581 (66) |
| BMI, kg/m2 | 29.6±6.6 |
| BMI ≥30 | 362 (41) |
| Ever smoking | 478 (53) |
| Current smoking | 178 (20) |
| ≥3 CAD risk factorsc | 609 (67) |
| Systolic blood pressure, mm Hg | 137±22 |
| Diastolic blood pressure, mm Hg | 76±11 |
| Total cholesterol, mg/dL | 195±45 |
| Triglycerides, mg/dL | 156±122 |
| HDL‐C, mg/dL | 54±13 |
| LDL‐C, mg/dL | 112±39 |
| Fasting glucose, mg/dL | 119±56 |
| Creatinine, mg/dL | 0.88±0.50 |
| Hemoglobin, g/dL | 12.9±1.3 |
| HOMA‐IR | 4.2±6.2 |
| Estimated GFR mL/min/1.73m2 | 95±39 |
| Ever HRT use | 455 (51) |
| Current HRT use | 343 (38) |
| Beta blockers | 353 (39) |
| Statins | 231 (26) |
| ACE inhibitors | 235 (26) |
| CAD status | |
| No CAD | 328 (36) |
| Minimal CAD | 223 (25) |
| Obstructive CAD | 353 (39) |
| Prior MI or revascularization | 257 (29) |
| Ejection fraction | 65±11 |
| Corrected QT interval, ms | 429±30 |
ACE indicates angiotensin‐converting enzyme; BMI, body mass index; CAD, coronary artery disease; GFR, glomerular filtration rate; HDL‐C, high‐density lipoprotein cholesterol; HOMA‐IR, homeostasis model assessment of insulin resistance; HRT, hormone replacement therapy; LDL‐C, low‐density lipoprotein cholesterol; MI, myocardial infarction.
a
Continuous variables are summarized as mean±1 SD, and qualitative variables summarized as n (%).
b
Age range is 21 to 86 years.
c
Includes diabetes mellitus, history of dyslipidemia, history of hypertension, family history of CAD, BMI ≥30, history of smoking, prior MI, or revascularization.