Table 4.
LSAC Wave 6 SEP Measures, at Age 10–11 Y | Mean Carotid IMT | Maximum Carotid IMT | ||
---|---|---|---|---|
Regression Coefficient, μm (95% CI) | P Value | Regression Coefficient, μm (95% CI) | P Value | |
Unadjusted | ||||
Family (per quartile lower) | 1.0 (−1.7, 3.7) | 0.46 | 3.7 (1.6, 5.8) | 0.001 |
Neighborhood (per quartile lower) | 1.3 (−1.5, 4.1) | 0.38 | 2.6 (0.4, 4.8) | 0.02 |
Model 1—age‐ and sex‐adjusted | ||||
Family (per quartile lower) | 1.1 (−1.6, 3.8) | 0.41 | 3.8 (1.6, 5.9) | 0.001 |
Neighborhood (per quartile lower) | 1.2 (−1.6, 4.0) | 0.40 | 2.6 (0.3, 4.8) | 0.02 |
Model 2—additional covariates | ||||
Family (per quartile lower) | 0.9 (−2.1, 3.9) | 0.56 | 3.3 (1.0, 5.7) | 0.005 |
Neighborhood (per quartile lower) | 0.5 (−2.5, 3.5) | 0.74 | 2.1 (−0.3, 4.4) | 0.08 |
Model 3—single model | ||||
Family (per quartile lower) | 0.8 (−2.3, 3.9) | 0.61 | 3.0 (0.6, 5.4) | 0.02 |
Neighborhood (per quartile lower) | 0.3 (−2.9, 3.4) | 0.87 | 1.2 (−1.3, 3.6) | 0.34 |
Regression coefficients are expressed as the μm difference in carotid IMT per quartile lower in SEP measure. Model 1 models were adjusted for age and sex, Model 2 for age, sex, body mass index z score, mean arterial blood pressure, pubertal category, minimal intima‐intima lumen diameter and exposure to passive smoking. The final Model 3 included both family and neighborhood SEP in the same model, along with all other covariates used in Model 2. Family SEP is a composite measure, standardized within each LSAC wave, summarizing parental education, occupation and household income. Neighborhood SEP uses Australian census‐derived data to generate a Socioeconomic Indexes For Areas (SEIFA) advantage/disadvantage score, according to family residential address postcode. CI indicates confidence interval; IMT, intima‐media thickness, LSAC, Longitudinal Study of Australian Children; SEP, socioeconomic position.