Table 4.

Comparison of Fractional Anisotropy Between Age Groups Stratified by WM Region

	3 Weeks		7 Weeks		P Value
	Mean	SD	Mean	SD
Deep WM	n=10		n=3
GCC	0.314	0.048	0.406	0.091	0.025a
BCC
Mean	0.365	0.046	0.407	0.010	0.148
Left	0.380	0.055	0.421	0.044	0.256
Right	0.349	0.047	0.393	0.030	0.147
SCC
Mean	0.320	0.037	0.380	0.067	0.049a
Left	0.313	0.038	0.395	0.051	0.008a
Right	0.327	0.041	0.365	0.083	0.258
ALIC
Mean	0.415	0.032	0.511	0.040	<0.001a
Left	0.413	0.036	0.494	0.035	0.004a
Right	0.418	0.035	0.528	0.045	<0.001a
PLIC
Mean	0.458	0.040	0.517	0.024	0.031a
Left	0.452	0.039	0.525	0.034	0.012a
Right	0.464	0.046	0.509	0.014	0.129
RLIC
Mean	0.505	0.044	0.495	0.046	0.717
Left	0.483	0.065	0.502	0.048	0.651
Right	0.528	0.035	0.488	0.048	0.124
M‐PVWM
Mean	0.375	0.033	0.428	0.010	0.019a
Left	0.378	0.037	0.454	0.030	0.006a
Right	0.371	0.037	0.403	0.014	0.179
L‐PVWM
Mean	0.439	0.043	0.479	0.009	0.140
Left	0.437	0.049	0.487	0.011	0.112
Right	0.441	0.048	0.472	0.027	0.312
PTR
Mean	0.445	0.039	0.509	0.010	0.016a
Left	0.421	0.038	0.493	0.026	0.009a
Right	0.470	0.048	0.526	0.019	0.072
SLF
Mean	0.303	0.033	0.325	0.025	0.326
Left	0.309	0.033	0.326	0.037	0.473
Right	0.297	0.038	0.323	0.014	0.278
CingWM
Mean	0.302	0.032	0.353	0.013	0.022a
Left	0.285	0.038	0.342	0.013	0.027a
Right	0.319	0.036	0.364	0.027	0.065
Superficial WM	n=10		n=3
SFWM
Mean	0.300	0.022	0.342	0.017	0.009a
Left	0.299	0.022	0.343	0.022	0.009a
Right	0.300	0.024	0.341	0.012	0.014a
MFWM
Mean	0.288	0.045	0.354	0.021	0.032a
Left	0.311	0.053	0.368	0.026	0.103
Right	0.264	0.062	0.340	0.022	0.063
IFWM
Mean	0.339	0.034	0.401	0.006	0.009a
Left	0.351	0.034	0.398	0.016	0.041a
Right	0.327	0.045	0.404	0.010	0.013a
PrCWM
Mean	0.305	0.037	0.339	0.032	0.161
Left	0.310	0.040	0.357	0.035	0.092a
Right	0.299	0.040	0.321	0.031	0.038a
SPWM
Mean	0.265	0.031	0.316	0.013	0.018a
Left	0.256	0.030	0.312	0.030	0.013a
Right	0.275	0.039	0.320	0.026	0.088

FA values are significantly different among WM regions analyzed (F=34.5, P<0.001) and at ages 3 weeks vs 7 weeks (F=72.4, P<0.001) by 2‐way ANOVA. ALIC indicates anterior limb of the internal capsule; BCC, body of the corpus callosum; CingWM, cingulum white matter; FA, fractional anisotropy; GCC, genu of the corpus callosum; IFWM, inferior frontal white matter; L‐PVWM, lateral periventricular white matter; MFWM, middle frontal white matter; M‐PVWM, medial periventricular white matter; PLIC, posterior limb of the internal capsule; PrCWM, pre‐central white matter; PTR, posterior thalamic radiation; RLIC, retrolenticular limb of the internal capsule; SCC, splenium of the corpus callosum; SFWM, superior frontal white matter; SLF, superior longitudinal fasciculus; SPWM, superior‐parietal white matter; WM, white matter.

^a P<0.05.