. 2017 Aug 3;6(8):e006028. doi: 10.1161/JAHA.117.006028

Table 2.

Number of 12‐Lead ECG Ectopic Beats as a Predictor of Outcomes in ARIC

Risk of Incident Atrial Fibrillation
Number of PACs on the Baseline 12‐Lead ECG	Unadjusted Analyses			Multivariable Adjusted Analyses^a
Number of PACs on the Baseline 12‐Lead ECG	HR	95% CI	P Value	HR	95% CI	P Value
1	2.8	2.2 to 3.6	<0.001	2.5	1.9 to 3.2	<0.001
2	2.4	1.3 to 4.3	0.004	1.8	1.0 to 3.2	0.075
>3	3.6	2.3 to 5.7	<0.001	3.0	1.9 to 4.8	<0.001

Risk of Incident Heart Failure
Number of PVCs on the Baseline 12‐Lead ECG	Unadjusted Analyses			Multivariable Adjusted Analyses^b
Number of PVCs on the Baseline 12‐Lead ECG	HR	95% CI	P Value	HR	95% CI	P Value
1	2.5	2.0 to 3.1	<0.001	1.8	1.5 to 2.3	<0.001
2	2.3	1.5 to 3.6	<0.001	1.6	1.0 to 2.5	0.032
>3	2.6	1.8 to 3.7	<0.001	2.0	1.4 to 2.9	<0.001

HR indicates hazard ratio; PAC, premature atrial contraction; PVC, premature ventricular contraction.

Adjusted for age, sex, race, body mass index, hypertension, diabetes mellitus, myocardial infarction, coronary artery disease, heart failure, and study site.

Adjusted for age, sex, race, body mass index, hypertension, diabetes mellitus, myocardial infarction, coronary artery disease, atrial fibrillation, and study site.