Table 4.
Multivariable Linear Regression Models for Coronary Artery Plaque Burden (log [PPS+1])
| Variable | All (β±SE) | Women (β±SE) | Men (β±SE) |
|---|---|---|---|
| Age, y | 0.058±0.002, P<0.0001 | 0.051±0.004, P<0.0001 | 0.064±0.003, P<0.0001 |
| Female sex | −0.512±0.024, P<0.0001 | ··· | ··· |
| eGFR, mL/min per 1.73 m2 | ··· | −0.004±0.002, P=0.0228 | 0.004±0.002, P=0.0285 |
| Heart rate, bpm | −0.006±0.002, P=0.0059 | −0.006±0.003, P=0.0384 | ··· |
| MAP, mm Hg | 0.005±0.002, P=0.0089 | ··· | 0.005±0.002, P=0.0685 |
| Hypertension | 0.134±0.025, P<0.0001 | 0.177±0.036, P<0.0001 | 0.114±0.0320, P=0.0004 |
| Hyperlipidemia | ··· | ··· | ··· |
| Diabetes mellitus | 0.113±0.033, P=0.0006 | 0.145±0.050, P=0.0040 | ··· |
| Smoking | 0.206±0.023, P<0.0001 | 0.227±0.034, P<0.0001 | 0.173±0.030, P<0.0001 |
| Antihypertensive use | ··· | ··· | ··· |
| Apirin use | ··· | ··· | 0.073±0.033, P=0.0255 |
| Statin use | 0.206±0.024, P<0.0001 | 0.182±0.036, P<0.0001 | 0.206±0.032, P<0.0001 |
| Log iAC | −0.105±0.077, P=0.1747 | −0.231±0.113, P=0.0418 | −0.062±0.104, P=0.5512 |
Results of step‐wise multivariable linear regression models with forward elimination, with criteria of P≤0.10 to enter and ≤0.05 to stay in the models. eGFR indicates estimated glomerular filtration rate; iAC, indexed arterial compliance; MAP, mean arterial pressure; PPS, percent plaque score.