Table 2.
Associationsa of Birth Weight for Length, Postnatal Weight Gain, and Childhood Adiposity With Plasma Lipids Measured at Ages 10–12 Years in 395 Children From the QUALITY Cohort, Quebec, Canada, 2005–2011
| Total Cholesterol | LDL Cholesterol | Triglycerides | HDL Cholesterol | |||||
|---|---|---|---|---|---|---|---|---|
| Model 1: adjusted for covariates | ||||||||
| Birth weight for length z score | −0.1 | (−1.8 to 1.6) | 0.2 | (−2.3 to 2.6) | −0.6 | (−5.2 to 3.9) | −0.6 | (−2.6 to 1.4) |
| Postnatal weight gain (0.5 weight‐for‐length z score from 0 to 2 y) | −0.3 | (−0.8 to 0.3) | −0.3 | (−1.1 to 0.5) | 1.4 | (−0.2 to 2.9) | −0.7 | (−1.4 to −0.007) |
| Model 2: adjusted for covariates and percentage of body fat | ||||||||
| Birth weight for length z score | −0.4 | (−2.1 to 1.3) | −0.4 | (−2.9 to 2.0) | −3.1 | (−7.5 to 1.3) | 0.4 | (−1.5 to 2.3) |
| Postnatal weight gain (0.5 weight‐for‐length z score from 0 to 2 y) | −0.4 | (−1.0 to 0.2) | −0.6 | (−1.5 to 0.2) | 0.1 | (−1.3 to 1.6) | −0.2 | (−0.8 to 0.5) |
| Percentage of total body fat (at ages 8–10 y) | 0.2 | (0.03 to 0.4) | 0.4 | (0.1 to 0.7) | 1.7 | (1.2 to 2.1) | −0.7 | (−0.9 to −0.5) |
CI indicates confidence interval; HDL, high‐density lipoprotein; LDL, low‐density lipoprotein; QUALITY, Quebec Adipose and Lifestyle Investigation in Youth.
Birth weight for length and postnatal growth in weight for length are entered simultaneously in model 1, and models are adjusted for child's age, sex, parental education, gestational age, breastfeeding, and in utero exposure to gestational diabetes mellitus, maternal hypertension, and maternal smoking. Model 2 is the same as model 1 but is further adjusted for percentage of total body fat mass. The β coefficients (95% CI) represent the percentage increase or decrease in the outcome for a 1‐U increase in the corresponding independent variable.