Skip to main content
. 2017 Aug 23;6(8):e006379. doi: 10.1161/JAHA.117.006379

Table 4.

Sensitivity Analysis of Random‐Effects Meta‐Analysis With Alternative Methods When Pooled Estimates Were From Combination of 2 Studies

Variable Random‐Effects Method Pooled OR 95% CI P Value
EAT measurement method
 EAT thickness27, 28 DL 3.09 0.56–17.01 0.20
HKSJ 3.09 0–19 0.49
Covariate modeling method
 EAT continuous21, 24 DL 1.18 0.77–1.81 0.44
HKSJ 1.18 0.08–18.5 0.58
 EAT per 10 mL25, 26 DL 1.18 1.12–1.24 <0.01
HKSJ 1.18 0.96–1.45 0.06a
HRP subtype
 LAP23, 24 DL 2.79 1.71–4.53 <0.01
HKSJ 2.79 0.59–13.2 0.08a
 PR23, 24 DL 1.93 1.25–2.99 0.003
HKSJ 1.93 0.77–4.84 0.07a
 Both LAP and PR23, 24 DL 2.58 1.55–4.28 <0.01
HKSJ 2.58 2.34–2.83 0.005

References indicate studies that were pooled. ORs are presented using DL and HKSJ methods. CI indicates confidence interval; DL, DerSimonian and Laird; EAT, epicardial adipose tissue; HKSJ, Hartung–Knapp–Sidik–Jonkman; HRP, high‐risk plaque; LAP, low attenuation plaque; OR, odds ratio; PR, positive remodeling.

a

Signifies when there was a change in P value resulting in statistical nonsignificance (P>0.05) after applying the HKSJ method.