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RS194B concentration dependence for reactivation at 37°C of macaque RBC-AChE and recombinant CHO-derived (rMaBChE) inhibited by a sarin analogue and paraoxon (POX) in vitro. (A) reactivation of isopropyl methylphosphonyl AChE from macaque blood MaRBC-AChE (B) reactivation of diethylphosphoryl Ma RBC AChE, (C) reactivation of isopropyl methylphosphonyl rMaBChE and (D) reactivation of diethylphosphoryl rMaBChE. Oxime was added at 0.5mM (grey), 1.5 mM (black), 5mM (red) and 15mM (blue).
