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. Author manuscript; available in PMC: 2017 Sep 6.
Published in final edited form as: Vet Pathol. 2016 Jan 20;53(4):754–763. doi: 10.1177/0300985815618439

Table 5.

Histologic Changes in Mice of Other Disease Models Experimentally Infected with MNV.a

Reference Mouse Strain MNV Strain Model Diet Liver MLN Aorta
12 B6.129P2-Apoetm1Unc/J MNV-4 Atherosclerosis Normal n/r n/r +
12 B6.129P2-Apoetm1Unc/J MNV-4 Atherosclerosis High fat, high cholesterol n/r n/r −
35 C57BL/6J MNV-4 Diet-Induced Obesity and Insulin Resistance High fat − + n/r
36 B6.129S7-Ldlrtm1her/J MNV-4 Atherosclerosis High fat, high sucrose n/r n/r −
36 B6.129S7-Ldlrtm1her/J MNV-4 Atherosclerosis High fat, high cholesterol n/r n/r +
37 B6.129S7-Ldlrtm1her/J MNV-4 Atherosclerosis High fat, high cholesterol n/r n/r −
Unpublished Apoe−/−/Tlr3−/− MNV-4 Atherosclerosis Normal n/r n/r −
a

+ = histologic changes reported, − = no histologic changes, n/r = not reported, MLN= mesenteric lymph node