Table 1.
Characteristics | All | QTc<450 ms | QTc≥450 ms |
---|---|---|---|
N visits (%) | 16,451 | 15,694 (95.4) | 757 (4.6) |
Age, yr | 60±11 | 60±11a | 62±9 |
Men, % | 53 | 54a | 40 |
Race/ethnicity, % | |||
Non-Hispanic white | 46 | 47a | 34 |
Non-Hispanic black | 40 | 40a | 52 |
Hispanic | 9 | 9b | 7 |
Other race/ethnicity | 4 | 4a | 7 |
Self-reported comorbidity, % | |||
MI/revascularization | 23 | 22a | 36 |
Congestive heart failure | 8 | 7a | 20 |
Diabetes | 47 | 47a | 56 |
Hypertension | 90 | 89a | 95 |
Stroke | 10 | 10a | 17 |
Current smoker, % | 11 | 11a | 15 |
Body mass index, kg/m2 | 31.9±7.8 | 31.8±7.7a | 33.9±8.4 |
eGFR, ml/min per 1.73 m2 | 42±15 | 42.6±15.1a | 37±16 |
Serum potassium, mmol/l | 4.4±0.5 | 4.4±0.5a | 4.1±0.6 |
Serum calcium, mg/dl | 9.3±0.5 | 9.3±0.5 | 9.1±0.7 |
Serum magnesium, mg/dl | 2.0±0.3 | 2.0±0.3c | 2.0±0.3 |
Systolic BP, mm Hg | 127±21 | 126±21a | 135±27 |
Diastolic BP, mm Hg | 70±13 | 70±12 | 70±15 |
Heart rate, min−1 | 65±11 | 65±11a | 63±10 |
QTc duration, ms | 414±21 | 413±17d | 462±16 |
Values expressed as mean±SD. Footnotes refer to comparisons according to QTc group. QTc, QT interval corrected for heart rate; MI, myocardial infarction.
P<0.001.
P<0.05.
Serum magnesium available only at baseline visit (n=3252 visits).
P value irrelevant (grouping variable).