Table 2.
Comparison of clinical features between XGC patients with and without GB cancer
| Item | XGC | XGC with GB cancer | p value |
|---|---|---|---|
| Patients | 62 | 6 | |
| Symptoms and signs | |||
| Abdominal pain | 46 (78.0%) | 2 (33.3%) | 0.1756 |
| Fever | 18 (30.5%) | 1 (16.7%) | 1.0000 |
| Jaundice | 10 (16.9%) | 3 (50%) | 0.0789 |
| Weight loss | 15 (25.4%) | 2 (33.3%) | 0.6352 |
| Laboratory findings | |||
| WBC/mm3 | 9,326 ± 2,564 | 8,321 ± 2,896 | 0.5440 |
| ALT, U/l | 75.2 ± 56.3 | 64.3 ± 25.9 | 0.1260 |
| Total bilirubin, mg/dl | 1.9 ± 2.3 | 2.8 ± 2.6 | 0.1630 |
| CA19-9 (>37 kU/l) | 22 (35.5%) | 6 (100%) | 0.0034 |
| CEA (positive) | 10 (16.1%) | 2 (33.3%) | 0.2846 |
| CT scan findings | |||
| Maximum thickness of GB wall, mm | 10.5 ± 4.6 | 11.2 ± 3.2 | 0.1530 |
| Focal thickening of GB wall | 17 (27.4%) | 5 (83.3%) | 0.0117 |
| Heterogeneous enhancement of the GB wall | 39 (62.9%) | 3 (50%) | 0.6827 |
| Early enhancement of GB wall | 21 (33.9%) | 5 (83.3%) | 0.0255 |
| Disrupted mucosal line | 26 (41.9%) | 4 (66.7%) | 0.3937 |
| Intramural hypoattenuated nodule | 32 (51.6%) | 3 (50%) | 1.0000 |
| Gallstone | 35 (56.4%) | 4 (66.7%) | 1.0000 |
| Pericholecystic invasion | 30 (48.4%) | 5 (83.3%) | 0.1978 |
| Lymph node enlargement (>10 mm) | 15 (24.2%) | 4 (66.7%) | 0.0471 |
| Surgical procedures | |||
| Open cholecystectomy | 26 (41.9%) | 0 | 0.0753 |
| Laparoscopic cholecystectomy | 23 (37.1%) | 0 | 0.0892 |
| Cholecystectomy and biliary tract exploration | 9 (14.5%) | 0 | 1.0000 |
| Cholecystectomy and partial hepatic wedge resection | 5 (8.1%) | 1 (16.7%) | 0.4383 |
| Radical correction of GB carcinoma | 0 | 5 (83.3%) | 0.0001 |
| Morbidity | 1 (1.6%) | 2 (33.3%) | 0.1690 |
| Wound infection | 1 | 1 | NA |
| Bile leakage | 0 | 1 | NA |
NA = Not applicable.