Table 3.

Mean serum levels of SP-D, sICAM-1 and hs-CRP in patients with COPD and controls

Groups/variables	Control (n = 26)		COPD patients (n = 64)
	control nonsmokers (n = 12)	control smokers (n = 14)	stage I (n = 10)	stage II (n = 17)	stage III (n = 17)	stage IV (n = 20)
SP-D, ng/ml	97.45±14.21	144.44±26.14	199.63±45.18	241.29±42.72	348.59±77.22	406.01±77.89
p1		0.038*	<0.001*	<0.001*	<0.001*	<0.001*
p2			0.021*	<0.001*	<0.001*	<0.001*
p3				0.068	<0.001*	<0.001*
p4					<0.001*	<0.001*
p5						0.003*
sICAM-1, ng/ml	99.65±2.36	103.42±1.66	116.55±16.60	122.36±9.08	163.74±46.29	173.38±34.92
p1		0.714	0.244	0.029*	<0.001*	<0.001*
p2			0.148	0.056	<0.001*	<0.001*
p3					<0.001*	<0.001*
p4					<0.001*	<0.001*
p5						0.382
hs-CRP, ng/ml	3626.36±355.55	4370.47±761.64	4,822.10±769.61	5,203.58±772.77	5,883.70±726.66	6,297.81±398.94
p1		0.005*	<0.001*	<0.001*	<0.001*	<0.001*
p2			0.096	0.001*	<0.001*	<0.001*
p3				0.143	<0.001*	<0.001*
p4					<0.001*	<0.001*
p5					0.003*	0.056

p1 = vs. control nonsmokers; p2 = vs. control smokers; p3 = vs. stage I; p4 = vs. stage II; p5 = vs. stage III. Data are expressed as mean ± SD; p values with an asterisk are significant.