Table 1.
Demographic and clinical features of SWAP-70 antibody-positive and SWAP-70 antibody-negative MS patients during attack and remission periods
| Attack |
Remission |
|||||
|---|---|---|---|---|---|---|
| SWAP-70 Ab+ (n = 16) | SWAP-70 Ab– (n = 10) | P value | SWAP-70 Ab+ (n = 9) | SWAP-70 Ab– (n = 17) | p value | |
| Female/male ratio | 9/7 | 10/0 | 0.0231 | 5/4 | 14/3 | 0.1881 |
| Age, years | 39.4 ± 2.6 | 40.0 ± 4.4 | 0.3362 | 38.0 ± 2.2 | 40.5 ± 4.1 | 1.0002 |
| Duration of MS, years | 9.2 ± 2.2 | 6.8 ± 0.9 | 0.4212 | 9.5 ± 2.8 | 7.7 ± 1.5 | 1.0002 |
| Annual attacks, n | 2.1 ± 0.1 | 2.5 ± 0.3 | 0.4572 | 2.2 ± 0.2 | 2.3 ± 0.2 | 1.0002 |
| EDSS | 2.4 ± 0.4 | 3.1 ± 0.3 | 0.1712 | 1.8 ± 0.2 | 2.9 ± 0.4 | 0.0732 |
| DMD, n | ||||||
| Interferon-β | 7 | 7 | 0.2471 | 4 | 10 | 0.6831 |
| Glatiramer acetate | 3 | 2 | 1.0001 | 1 | 4 | 0.6281 |
| Others | 6 | 1 | 0.1911 | 4 | 3 | 0.1881 |
Values are presented as means ± SE unless otherwise specified. Ab = Antibody; DMD = disease-modifying drug.
1
Fisher's exact test.
1
Mann-Whitney U test.