Table 1.
Antimicrobial activity on some of the oral pathogens clinically isolated by agar disk diffusion test
| S. pyogenes (n = 20) | S. mutans (n = 30) | C. albicans (n = 20) | A. actinomycetemcomitans (n = 30) | P. gingivalis (n = 30) | |
|---|---|---|---|---|---|
| MCO | |||||
| 3.9 ॖg/ml | R | R | R | R | R |
| 7.8 ॖg/ml | 8.3 ± 0.5 | R | R | R | R |
| 15.6 ॖg/ml | 9.9 ± 0.8 | R | R | R | R |
| 31.25 ॖg/ml | 11.8 ± 0.9 | 8.8 ± 1.2 | R | R | R |
| 62.5 ॖg/ml | 15.9 ± 0.9 | 10.0 ± 0.9 | 8.1 ± 1.2 | R | R |
| 125 ॖg/ml | 20.8 ± 0.4 | 15.8 ± 0.6 | 9.9 ± 0.8 | 8.8 ± 0.3 | 8.1 ± 1 |
| 250 ॖg/ml | 28.3 ± 0.6 | 21.0 ± 0.6 | 17.4 ± 0.6 | 15.8 ± 0.5 | 11.8 ± 0.9 |
| 500 ॖg/ml | 34.2 ± 0.4 | 28.7 ± 0.7 | 24.2 ± 0.5 | 20.4 ± 0.9 | 17.2 ± 0.3 |
| 1,000 ॖg/ml | 41.25 ± 0.8 | 38.8 ± 0.9 | 31.4 ± 0.7 | 29.4 ± 0.6 | 24.3 ± 0.7 |
| Antbiotic disks1 | |||||
| Vancomycin | 21.5 ± 0.8 | 21.2 ± 0.9 | R | R | R |
| Amikacin | R | R | R | 9.8 ± 0.7 | 9.1 ± 0.2 |
| Nystatin | R | R | 18.02 ± 0.8 | R | R |
| 10% DMSO | R | R | R | R | R |
Figures show the inhibition zone diameter in mm (mean ± SD). R = Resistant (no inhibition zones)
1
Vancomycin: 30 ॖg, amikacin: 30 ॖg and nystatin: 25 ॖg.