Table 2.
Total IgE and A fum-specific antibodies
| Variables | Control | COPD | P-values |
|---|---|---|---|
| Patients (n) | 50 | 300 | |
| Total IgE, kU/L | 42.5 (16.5–105.5) | 52.0 (17.0–198.5) | 0.3068 |
| Total IgE >114, kU/L (%) | 11 (22) | 103 (34.3) | 0.0849 |
| A fum extract IgE (%) | 1 (2) | 31 (10.3) | 0.0584 |
| rAsp f1 IgE (%) | 1 (2) | 36 (12) | 0.0332 |
| rAsp f2 IgE (%) | 1 (2) | 7 (2) | 0.8839 |
| rAsp f3 IgE (%) | 1 (2) | 20 (6.7) | 0.1983 |
| rAsp f4 IgE (%) | 0 (0) | 3 (1) | 0.4776 |
| rAsp f6 IgE (%) | 0 (0) | 4 (1.3) | 0.4115 |
| Sensitized in total (%)a | 2 (4) | 55 (18.3) | 0.0110 |
| A fum IgG, mg/L | 20.7 (9.6–42.8) | 31.0 (15.9–48.5) | 0.0473 |
Notes: Data are presented as n, median (interquartile range) or n (%). P-values <0.05 are shown in bold.
a
Sensitization to at least one of the A fum allergens including the extract.
Abbreviations: COPD, chronic obstructive pulmonary disease; A fum, Aspergillus fumigatus; rAsp f1, A fum recombinant f1; rAsp f2, A fum recombinant f2; rAsp f3, A fum recombinant f3; rAsp f4, A fum recombinant f4; rAsp f6, A fum recombinant f6.