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Effect of CPAP withdrawal on glucose kinetics in patients receiving 6,6-[2H2] glucose. (a) Plasma glucose, insulin, rate of glucose appearance (Ra), disappearance (Rd), or MCR were unchanged (n = 11). (b) In patients who exhibited OSA-induced hyperglycemia (n = 4), there was no increase in glucose production but a fall in MCR and an early and persistent rise in insulin, suggesting peripheral insulin resistance.
