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. 2017 Jun 9;102(9):3261–3267. doi: 10.1210/jc.2017-00158

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Figure 4. — Expression profiles for insulin and somatostatin in mosaic islets. No quiescent islets from CHI-A tissue were composed of >60% β-cells (INS⁺) (n = 70 islets). For comparison, >97% of active islets (n = 70) from the same tissues (n = 3 patients), 100% of age-matched control pancreata (n = 70 islets; n = 3 donors), and 93% of CHI-D tissues (n = 72 islets; n = 3 patients) were composed of >60% β-cells. In quiescent tissue, 85% of the islets (n = 57) were composed of >20% δ-cells compared with 13% of active islets from the same tissue (n = 3 cases; n = 46 islets), 5% of control islets (n = 3 cases; n = 60 islets), and 12% of CHI-D islets (n = 3 patients; n = 66 islets).