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(A) Screening results for spheroid cultures exposed to common chemotherapy drugs and combinations from five patients. ED25: the dose at which a given drug resulted in 25% growth reduction compared to untreated spheroids. * poor curve fit, however, max growth reduction was 17% so ED25 was assigned >500nM. (B) Curve fit graphs for Pt.20 and Pt.21 demonstrating different chemosensitivity profiles.
