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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Behav Brain Res. 2016 Nov 3;319:96–103. doi: 10.1016/j.bbr.2016.10.050

Figure 4.

Figure 4

Treatment with the MOR antagonist cyprodime (10 mg/kg, i.p.) reduced approach latency and increased food consumption in the NIH test 1 h post administration. A) A dose response curve revealed that at 1 h post administration 10 mg/kg, but not 3 mg/kg, cyprodime significantly reduced approach latency and B) increased the amount of food consumed. N = 10–30 per group. C) In a separate cohort of animals 10 mg/kg cyprodime tested 24 h later did not exhibit any changes approach latency or D) food consumed compared to vehicle treated animals. N = 10 per group. (*p < 0.05, **p < 0.01 compared to vehicle).