Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 31;12:6399–6412. doi: 10.2147/IJN.S144033

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Sun et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Metastatic significance of concomitant CTC count, serum MMP7 expression, and serum MMP9 expression.

Notes: The cutoff values for CTC number, serum MMP7 level, and serum MMP9 level had great sensitivity and specificity for metastasis, with an area under the curve (AUC) of (A) 0.945 (95% CI: 0.900–0.990; p<0.01), (B) 0.949 (95% CI: 0.913–0.986; p<0.01), and (C) 0.930 (95% CI: 0.881–0.979; p<0.01), respectively. (D) The predicted cutoff value of the combination of CTC count, serum MMP7 level, and serum MMP9 level had an optimal AUC of 0.950 (95% CI: 0.909–0.992; p<0.01).

Abbreviations: CTC, circulating tumor cell; MMP7/9, matrix metalloproteinase 7/9.