Table 5.

Birth outcomes as predictors of continuous liver enzymes (log-transformed, within the normal range), Cardiovascular Risk in Young Finns Study

	Model 1			P for interaction	Model 2			P for interaction
	Unadjusted				Adjusted for age, sex, race, smoking, alcohol use, education, income, physical activity
	βa	SE	P		β	SE	P
γ-glutamate transferase (GGT)
Men
Small-for-gestational-age	0.01	0.05	0.79	0.19	0.00	0.05	0.96	0.08
Large-for-gestational-age	−0.03	0.05	0.61	0.64	−0.02	0.05	0.66	0.46
Preterm birth	0.13	0.08	0.09	0.02	0.10	0.07	0.18	0.04
Women
Small-for-gestational-age	0.08	0.00	<0.01		0.09	0.03	<0.01
Large-for-gestational-age	−0.05	0.03	0.06		−0.06	0.03	0.03
Preterm birth	−0.06	0.04	0.15		−0.06	0.04	0.17
Alanine transaminase (ALT)
Men
Small-for-gestational-age	0.06	0.05	0.22	0.91	0.04	0.05	0.38	0.98
Large-for-gestational-age	−0.01	0.05	0.80	0.78	−0.01	0.05	0.82	0.77
Preterm birth	0.15	0.07	0.03	<0.01	0.14	0.07	0.05	<0.01
Women
Small-for-gestational-age	0.05	0.03	0.06		0.05	0.03	0.09
Large-for-gestational-age	0.00	0.03	0.93		0.01	0.03	0.71
Preterm birth	−0.07	0.04	0.10		−0.06	0.04	0.13
Aspartate transaminase (AST)
Men
Small-for-gestational-age	0.02	0.02	0.36	0.37	0.02	0.02	0.38	0.32
Large-for-gestational-age	−0.01	0.03	0.80	0.42	−0.03	0.03	0.26	0.22
Preterm birth	0.07	0.04	0.06	0.27	−0.01	0.03	0.65	0.22
Women
Small-for-gestational-age	0.05	0.02	<0.01		0.05	0.02	<0.01
Large-for-gestational-age	0.02	0.02	0.26		0.02	0.02	0.23
Preterm birth	0.02	0.03	0.51		0.01	0.03	0.69
Fatty liver index (FLI)a
Men
Small-for-gestational-age	0.86	3.09	0.78	0.85	−0.91	2.85	0.75	0.37
Large-for-gestational-age	7.33	3.23	0.02	0.01	5.30	2.96	0.07	0.03
Preterm birth	1.35	4.49	0.76	0.96	0.93	4.21	0.83	0.96
Women
Small-for-gestational-age	1.56	2.01	0.44		2.03	1.96	0.30
Large-for-gestational-age	−2.33	1.98	0.24		−1.90	1.98	0.34
Preterm birth	1.61	3.10	0.60		1.86	3.12	0.55
	Model 3			P for interaction
	Previous +BMI
	β	SE	P
γ-glutamate transferase (GGT)
Men
Small-for-gestational-age	0.02	0.05	0.68	0.14
Large-for-gestational-age	−0.05	0.05	0.29	0.81
Preterm birth	0.12	0.07	0.07	0.01
Women
Small-for-gestational-age	0.09	0.03	<0.01
Large-for-gestational-age	−0.05	0.03	0.05
Preterm birth	−0.06	0.04	0.11
Alanine transaminase (ALT)
Men
Small-for-gestational-age	0.06	0.04	0.17	0.94
Large-for-gestational-age	−0.05	0.05	0.29	0.56
Preterm birth	0.16	0.07	0.02	<0.01
Women
Small-for-gestational-age	0.06	0.03	0.04
Large-for-gestational-age	0.00	0.03	0.90
Preterm birth	−0.07	0.04	0.07
Aspartate transaminase (AST)
Men
Small-for-gestational-age	0.03	0.02	0.26	b
Large-for-gestational-age	−0.02	0.03	0.36	0.03
Preterm birth	0.08	0.04	0.04	0.96
Women
Small-for-gestational-age	0.05	0.02	<0.01
Large-for-gestational-age	0.02	0.02	0.24
Preterm birth	0.01	0.03	0.65
Fatty liver index (FLI)	BMI included in measurement

^aNot log-transformed.

^bInteraction model failed to converge.