Table 4.

Risk of Incident VTE, PE and DVT in GCA According to Age Group and Sex

	Overall		Age < 75 years		Age ≥ 75 years		Men		Women

	GCA (N= 909)	Non-GCA (n=9,288)	GCA (n=322)	Non-GCA (n=3,376)	GCA (n= 587)	Non-GCA (n=5,912)	GCA (n= 242)	Non-GCA (n= 2,468)	GCA (n= 667)	Non-GCA (n= 6,820)
VTE
Cases	31	121	9	30	22	91	10	29	21	92
Incidence rate/1000 PY	13.26	3.70	9.47	2.60	15.86	4.30	18.26	3.32	11.73	3.84
Multivariable HR ^a (95% CI)	2.49 (1.45–4.30)	1.0	2.44 (0.81–7.31)	1.0	2.69 (1.43–5.07)	1.0	4.29 (1.45–12.73)	1.0	2.19 (1.17–4.10)	1.0
PE
Cases	18	63	4	16	14	47	4	13	14	50
Incidence rate/1000 PY	7.65	1.92	4.20	1.38	9.99	2.21	7.2	1.5	7.81	2.08
Multivariable HR^a (95% CI)	2.71 (1.32–5.56)		2.10 (0.43–10.30)	1.0	2.97 (1.30–6.78)	1.0	4.74 (1.28–17.53)	1.0	2.33 (1.03–5.29)	1.0
DVT
Cases	20	73	8	18	12	55	7	18	13	55
Incidence rate/1000 PY	8.52	2.22	8.40	1.55	8.61	2.59	12.78	2.06	7.23	2.29
Multivariable HR^a (95% CI)	2.78 (1.39–5.54)		3.0 (0.83–10.87)	1.0	2.85 (1.22–6.69)	1.0	4.74 (1.28–17.53)	1.0	2.33 (1.03–5.29)	1.0

DVT, Deep vein thrombosis; GCA, Giant cell arteritis; HR, hazard ratio; PE, Pulmonary embolism