Table 5.
Sensitivity Analyses on the risk of VTE in patients with Giant Cell Arteritis
| Primary Analysis(N= 909) HR (95%CI) |
Sensitivity Analysis 1(N= 909) HR (95%CI) |
Sensitivity Analysis 2(N= 593) HR (95%CI) |
Sensitivity Analysis 3(N= 909) HR (95%CI) |
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|---|---|---|---|---|---|---|---|
|
| |||||||
| Prevalence = 10%a ORb = 1.3 |
Prevalence = 10% a ORb = 3.0 |
Prevalence = 20% a ORb = 1.3 |
Prevalence = 20% a ORb = 3.0 |
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| VTE | 2.49 (1.45–4.30) | 2.15 (1.29–3.56) | 2.43 (1.33–4.43) | 2.44 (1.41–4.19) | 2.05 (1.20–3.52) | 2.49 (1.44–4.29) | 1.88 (1.07–3.28) |
| PE | 2.71 (1.32–5.56) | 2.34 (1.15–4.76) | 2.48 (1.11–5.52) | 2.61 (1.27–5.37) | 2.15 (1.05–4.38) | 2.65 (1.29–5.45) | 1.89 (0.90–3.96) |
| DVT | 2.78 (1.39–5.54) | 2.30 (1.25 (4.22) | 2.88 (1.35–6.16) | 2.68 (1.34–5.34) | 2.38 (1.20–4.70) | 2.87 (1.43–5.77) | 2.13 (1.05–4.33) |
DVT, Deep vein thrombosis; HR, Hazard ratio; OR, Odds ratio; PE, Pulmonary embolism; VTE, Venous thromboembolism
hypothetical prevalence of the unmeasured confounder in the giant cell arteritis cases
hypothetical level of association between the unmeasured confounder and the outcome
Sensitivity analyses 1; accounting for the competing risk of death
Sensitivity analyses 2; limited to giant cell arteritis cases that received at least 5 prescriptions for oral glucocorticoids during follow-up
Sensitivity analyses 3; accounting for unmeasured confounders