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. Author manuscript; available in PMC: 2017 Sep 6.
Published in final edited form as: J Am Chem Soc. 2017 Jun 6;139(24):8126–8129. doi: 10.1021/jacs.7b04937

Scheme 4.

Scheme 4

The use of (a) acrylic acid and (b) β-ethoxyacrylic acid to access chiral ethyl ketones.a

a Yields represent average isolated yields of two runs, performed with 1 mmol of alkene.