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. 2017 Sep 6;12(9):e0182810. doi: 10.1371/journal.pone.0182810

Fig 3.

Fig 3

(A). Glucose levels of young ZDF rats and age-matched lean controls used for the study. Daily mean glucose levels of ZDF rats or controls from the age of 38 days through the age of 48 days were plotted. N = 4 rats/grouop. D38-41, age Day 38 to Day 41; D42-48, age Day 42 to Day 48. Glucose levels were not significantly different between ZDF rats and lean controls during the age of Day 38 to Day 41 (D38-41) but were statistically different during the age of Day 42 to Day 48 (D42-48). (B). Reduced multiscale entropy in ZDF rats compared with age-matched controls when glucose levels were not different at the age of D38-41. (C). Further decline of multiscale entropy in ZDF rats compared with age-matched controls during the transition to hyperglycemia at the age of D42-48. The P values in Fig 3B and 3C were calculated by performing unpaired t-tests for differences in mean sample entropy between the two groups of mice at the times scales indicated.