Table 5.
Area under curve (AUC) of Corneal Visualization Scheimpflug Technology (Corvis ST) parameters with their standard error (SE), 95% confidence interval (CI), and their best cut-offs for optimizing sensitivity and specificity to separate normal and keratoconic corneas in two central corneal thickness (CCT) controlled subgroups.
| Variable | Cut-off point | Sensitivity (%) | Specificity (%) | AUC | SEa | 95% CIb |
|---|---|---|---|---|---|---|
| A1T (ms) | ≤7 | 90 | 90 | 0.904 | 0.0545 | 0.768–0.974 |
| A2T (ms) | >21.4 | 70 | 100 | 0.879 | 0.0538 | 0.737–0.960 |
| A2V (m/s) | ≤−0.37 | 75 | 75 | 0.737 | 0.0822 | 0.575–0.864 |
| HCDA (mm) | >1.1 | 55 | 100 | 0.794 | 0.0720 | 0.636–0.905 |
| HCR (mm) | ≤6.13 | 65 | 100 | 0.821 | 0.0703 | 0.668–0.924 |
AUC: Area under curve; SE: Standard error; CI: Confidence interval; A1T: First applanation time; A2T: Second applanation time; A2V: Second applanation velocity; HCDA: Highest concavity deformation amplitude; HCR: Highest concavity radius.
a
DeLong et al., 1988.
b
Binomial exact.