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. 2017 Sep 6;12(9):e0184068. doi: 10.1371/journal.pone.0184068

Fig 3. Tankyrase inhibitors decrease mRNA expression of YAP target genes in HCC cell lines.

Fig 3

qRT-PCR analysis of mRNA expression of CTGF, Cyr61, and YAP in SNU-449 (A) and HLE (B) HCC cell lines upon treatment with XAV-939 and G007-LK inhibitors. Student’s t-test: (a) p<0.05 vs. DMSO; (b) p<0.01 vs. DMSO. qRT-PCR experiments were repeated three times.