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. 2017 Sep 6;12(9):e0184338. doi: 10.1371/journal.pone.0184338

Fig 1. ROC curves of SUVmax, each tumor marker, combined tumor markers and the combination of both methods in evaluation of different histological types.

Fig 1

ROC curves of SUVmax, each tumor marker, combined tumor markers and the combination of both methods in differentiating between lung cancers and benign lesions (A) and between NSCLC and SCLC (B). When SUVmax and tumor markers were combined, the AUC, sensitivity and specificity increased significantly. ROC: Receiver operating characteristic, CEA: carcino embryonie antigen, CYFRA21-1: cytokeratin 19 fragments, SCC-Ag: squmaous cell carcinoma antigen, NSE: neuron specific enolase, SUVmax: maximal standard uptake value, SCLC: small-cell lung carcinoma, NSCLC: non-small-cell lung carcinoma, AUC: areas under the curve.