Skip to main content

Table 1.

Drosophila and vertebrate polarity proteins described in this review

Drosophila protein Vertebrate ortholog/paralog Alias
Apicobasolateral polarity proteins
Crumbs CRB1- 3
Stardust MPP5 PALS1
Discs lost INADL; MUPP1 PATJ
Atypical protein kinase C PRKCi; PRKCz aPKC
Bazooka PARD3, 3B Par3
Par-6 PARD6A,B,G
Cdc42 CDC42
Scribble SCRIB
Discs large DLG1- 5
Lethal giant larvae LLGL1-2
Par-1 MARK3; MARK2
14-3-3ɛ/ζ YWHAZ; YWHAE Par5
Yurt EPB41L5 Band 4.1 like 5
Coracle EPB41 Band 4.1
ATPα/β ATP1A1-4; ATP1B1 Sodium potassium ATPase
Nrx-IV CNTNAP1 Neurexin-4
Lkb1 kinase STK11 Lkb1/Par4
Planar cell polarity proteins
Flamingo CELSR1-3
Van Gogh VANGL1-2
Prickle PRICKLE1-4
Frizzled FZD
Diego INVS; DIV Inversin; diversin
Dishevelled DVL1-3
- PTK7 Protein tyrosine kinase 7
Secretory 24AB SEC24B
Scribble SCRIB
Fat FAT1-4
Daschous DCHS1-2 Protocadherin-16; protocadherin-23
Four jointed FJX1
Inturned INTU
Fuzzy FUZ
Fritz WDPCP BBS15
Flattop CFAP126
Inscuteable INSC
Partner of Inscuteable GPSM2 LGN
Gαi GNAI