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. 2017 Mar 6;34(1):13–21. doi: 10.1007/s12264-017-0106-5

Fig. 4.

Fig. 4

CCL2 enhances NMDAR-mediated synaptic currents in lamina IIo neurons evoked by dorsal root stimulation of spinal cord slices. A Traces of evoked NMDAR-mediated and AMPAR-mediated currents (eEPSC) before and after CCL2 treatment (100 ng/mL, 2 min). B Amplitude of NMDAR-mediated and AMPAR-mediated currents (eEPSC). *P < 0.05, paired two-tailed Student’s t test; n = 5–6 neurons/group; n.s., not significant. Note that CCL2 only enhanced NMDAR-mediated but not AMPAR-mediated synaptic currents. The data are expressed as mean ± SEM.