Table 4.

Characteristics of 19 ALI subjects who died within 21 days of enrollment

ALI etiology	Progression to ALF	Time from enrollment to death (days)	Cause of death
1. APAP	No	2	Cardiac arrest
2. Hepatitis B	Yes	3	Multisystem organ Failure/sepsis
3. Shock/ischemia	Yes	11	Unknown
4. Autoimmune hepatitis	Yes	16	Unknown
5. DILI	Yes	8	Multisystem organ failure
6. APAP	Yes	8	Neurological (cerebral edema)
7. Indeterminate	No	1	Unknown
8. Indeterminate	Yes	11	Neurological (cerebral edema)
9. APAP	No	8	Pulmonary embolism
10. Autoimmune hepatitis	Yes	7	Liver failure
11. Indeterminate	Yes	4	Multisystem organ failure/sepsis
12. Autoimmune hepatitis	No	13	Multisystem organ Failure
13. Autoimmune hepatitis	Yes	4	PEA arrest
14. Shock/ischemia	No	14	Multisystem organ failure
15. APAP	No	10	Liver failure
16. Hepatitis B	No	9	Liver failure
17. Indeterminate	No	18	Unknown
18. Hepatitis B	No	20	Liver failure
19. Autoimmune hepatitisa	Yes	17	Intracardiac thrombosis

ALI, acute liver injury; ALF, acute liver failure; APAP, N-acetyl-p-aminophenol; DILI, drug-induced liver injury; PEA, pulseless electrical activity.

^aPatient died shortly after liver transplant.