Table 2.

Distance run, location, and task compliance of mice during weekly treadmill fatigue tests.

	Week	PBS (n=12)	TAL (n=11)	MPH (n=11)	Main effect of treatment
					F value	P value
Distance (m)	1	296 ± 52	779 ± 118**	333 ± 66	F(2,31) = 10.64	P = 0.0003
	2	443 ± 104	954 ± 110**	228 ± 78	F(2,31) = 13.96	P < 0.0001
	3	247 ± 92	837 ± 156**	172 ± 57	F(2,31) = 10.99	P = 0.0002
	4	129 ± 54	907 ± 157**	278 ± 311	F(2,31) = 14.60	P < 0.0001
Location	1	2.1 ± 0.11	2.9 ± 0.03***	2.5 ± 0.12*	F(2,31) = 17.62	P < 0.0001
	2	2.1 ± 0.16	2.9 ± 0.04***	2.3 ± 0.10	F(2,30) = 14.36	P < 0.0001
	3	1.9 ± 0.22	2.7 ± 0.15*	2.2 ± 0.12	F(2,29) = 5.175	P = 0.0120
	4	1.9 ± 0.30	2.9 ± 0.06*	2.2 ± 0.12	F(2,26) = 10.45	P = 0.0005
Number of Non-Runners	1	1	0	2
	2	2	0	4
	3	6	1	3
	4	7	1	3

Data for the PBS group in this table were previously published and reproduced with permission from ref 30.

^*P < 0.05,

^**P < 0.01,

^***P < 0.001 compared to PBS, post-hoc t-tests with a Holm-Bonferroni correction.