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. Author manuscript; available in PMC: 2017 Nov 24.
Published in final edited form as: Nature. 2017 May 24;546(7657):248–253. doi: 10.1038/nature22394

Extended Data Figure 5. A near-atomic resolution model of the hGLP-1:rGLP-1R:Gs complex.

Extended Data Figure 5

EM density map and model are shown for all seven TMs and H8 of rGLP-1R, hGLP-1 peptide and GαsRas α5-helix. Bulky resides are indicated for each segment. The C-terminal half of TM6 exhibits relatively poor density, reflecting its intrinsic flexibility.