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. Author manuscript; available in PMC: 2017 Nov 24.
Published in final edited form as: Nature. 2017 May 24;546(7657):248–253. doi: 10.1038/nature22394

Extended Data Figure 2. Cryo-EM micrograph and 2D class averages of the hGLP-1:rGLP-1R:Gs complex.

Extended Data Figure 2

a, Cryo-EM micrograph of the activated GLP-1R:Gs complex. Examples of sample particle projections are circled (scale bar: 30 nm). b, Representative reference-free two-dimensional averages show distinct secondary structure features for G protein and GLP-1R embedded in MNG detergent micelle. The diameter of the circular windows is 17 nm.