Table 5. Correlation between plaque characteristics and clinical parameters.

	Plaque burden				Fibrotic components
	Univariate		Multivariate		Univariate		Multivariate
	r	p	β	p	r	p	β	p
Age	−0.050	0.751			−0.081	0.606
BMI	0.474	0.002	0.369	0.018	−0.115	0.468
Systolic blood pressure	−0.313	0.041	−0.194	0.168	−0.056	0.720
Diastolic blood pressure	−0.072	0.645			−0.055	0.728
Fasting blood sugar	0.029	0.854			−0.301	0.050	−0.085	0.581
IRI	0.111	0.491			−0.248	0.117
HOMA-R	0.110	0.495			−0.261	0.100
HbA1c (NGSP)	−0.073	0.643			−0.069	0.663
Total cholesterol	0.005	0.976			−0.117	0.462
Triglyceride	0.164	0.293			−0.249	0.107
HDL-C	−0.290	0.060			0.012	0.940
LDL-C	0.158	0.317			−0.030	0.851
hsCRP	0.138	0.398			0.154	0.343
serum creatinine	−0.075	0.633			0.073	0.641
eGFR	0.071	0.652			−0.069	0.661
CysC	−0.064	0.682			−0.002	0.990
APN	−0.317	0.039	−0.201	0.190	0.123	0.431
CysC–APN complex	−0.020	0.899			−0.384	0.011	−0.285	0.069

	Necrotic components				Lipidic plus Necrotic components
	Univariate		Multivariate		Univariate		Multivariate
	r	p	β	p	r	p	β	p
Age	0.027	0.865			0.040	0.797
BMI	0.152	0.337			0.169	0.286
Systolic blood pressure	0.053	0.737			0.032	0.838
Diastolic blood pressure	0.051	0.746			0.031	0.842
Fasting blood sugar	0.352	0.021	0.120	0.433	0.313	0.041	0.009	0.572
IRI	0.230	0.149			0.292	0.064
HOMA-R	0.262	0.098			0.305	0.053
HbA1c (NGSP)	0.099	0.529			0.054	0.732
Total cholesterol	0.147	0.355			0.136	0.389
Triglyceride	0.287	0.062			0.277	0.072
HDL-C	0.028	0.860			−0.011	0.942
LDL-C	0.039	0.809			0.045	0.779
hsCRP	−0.196	0.226			−0.145	0.373
serum creatinine	−0.150	0.339			−0.121	0.438
eGFR	0.148	0.343			0.122	0.436
CysC	−0.064	0.682			−0.002	0.990
APN	−0.171	0.273			−0.179	0.251
CysC–APN complex	0.406	0.007	0.276	0.076	0.417	0.005	0.287	0.067

The relationships among parameters were investigated by Spearman's correlation coefficient (univariate) and multiple regression analysis (multivariate).