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. 2017 Jul 1;25(13):3471–3482. doi: 10.1016/j.bmc.2017.04.037

Scheme 3.

Scheme 3

(a) CH2Cl2, Py, Tf2O, (b) ArB(OH)2, LiCl, DCE, Pd(PPh3)4, (c) compounds 10, 1215: RNH2, DCE, NaBH(OAc)3, (d) compounds 11, 1618: RNH3+, MeOH, Et3N, NaBH(OAc)3, (e) Et2O, 2 M HCl in Et2O. General procedures are detailed in the Supporting information.