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. 2017 Jul 1;25(13):3471–3482. doi: 10.1016/j.bmc.2017.04.037

Table 3.

Structures and IC50 of the final linked compounds.

graphic file with name fx17.jpg

Compound Structure Kd IC50 PDB
21 graphic file with name fx18.gif 1.64 n/a 5MO8
CAM4066 graphic file with name fx19.gif 0.320 0.370 5CU4
Pre-CAM4066 graphic file with name fx20.gif n/a n/a N/D