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. 2017 Sep 6;7:10721. doi: 10.1038/s41598-017-10817-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Overview of representative AVNFH and control bone samples used in the study. (A) A representative gross image of a trabecular cross section of control bone. (B) Same as in A, but for AVNFH bone. Region affected by AVN is shown by the yellow arrow. (C) X ray image of the pelvic region from a control individual with fractured femur (D) X ray image of the pelvic region of a patient with Avascular Necrosis of the Femoral Head (AVNFH). (E,F) Magnetic Resonance Image (MRI of the pelvic region of a patient with AVNFH.