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. 2017 Sep 6;7:10721. doi: 10.1038/s41598-017-10817-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Representative Scanning Electron Microscopic (SEM) images of control and AVNFH bone. (A–C) SEM images of control bone showing honey comb shaped trabecular arrangement. Regions of bone remodelling is also observed (red arrow). (D–F) SEM images of AVNFH bone showing perturbed trabecular arrangement. Trabeculae lose connectivity altering the honey comb shape. In addition, regions of dead bones are observed. (Black areas indicated by red arrow). Extensive remodelling of the bone is indicated by red arrows.