Table 1.

Pathway analysis for the p53-induced and p53-repressed genes.

	Term	Genes	−log (p value)	Fold enrichment
p53-induced genes	p53 signalling pathway	P21, Bbc3, Z3, Bax, Rprm, Mdm2, Pmaip1, Fas, Perp, Sesn2, Ccng1	12.27	30.49
	Cytokine-cytokine receptor interaction	Inhbb, Tnfrsf10b, Gdf5, Eda2r, Fas, Cd137l	2.16	4.7
	TGF-beta signalling pathway	Inhbb, Gdf5, Fst	1.15	6.6
	Apoptosis	Tnfrsf10b, Bax, Fas	1.15	6.6
p53-repressed genes	Cell cycle	Cdk1, E2f2, Cdc6, Ttk, Chek1, Mcm2, Mcm3, Mcm5, Mcm6, Ccne2, Cdc45, Ccnb2, Plk1, Bub1, Bub1b, Ccna2	10.99	21.1
	DNA replication	Prim1, Dna2, Pole, Mcm2, Mcm3, Mcm5, Mcm6	5.70	33.75
	Oocyte meiosis	Ccne2, Cdk1, Ccnb2, Plk1, SgoL1, Bub1, Fbxo5	2.82	10.27
	p53 signalling pathway	Ccne2, Cdk1, Ccnb2, Rrm2, Chek1	2.44	12.23
	Progesterone-mediated oocyte maturation	Cdk1, Ccnb2, Plk1, Bub1, Ccna2	1.81	9.93
	Pyrimidine metabolism	Prim1, Rrm2, Pole, Tk1	1.54	7.03